Recent years have witnessed an increased interest from pediatric neurologists,neuropediatricians,epilep-tologists and general neurologists in the use of the ketogenic diet (KD) for the management of refractory epilepsies. In parallel with this interest, a number of studies have been completed addressing a wide range of issues related to this diet, from its mechanisms of action in animal models to its efficacy and tolerability profiles in different populations of patients. In recognition of this, the Institute of Neurology IRCCS C.
Mondino Foundation in Pavia, Italy, took the initiative of organizing, on 24 September 2005, an international workshop whose purposes were to discuss the rationale for the use of the KD, and bridge basic science data with evidence from clinical experience; review critically and update current acquisitions on the use of the diet in the epilepsies; highlight controversies concerning indications and modes of application; identify areas and methodology for future research.
The workshop, which was attended by many leading experts from both sides of the Atlantic, provided a forum for constructive interaction between many disciplines which contribute to our knowledge in this area. The purpose of this manuscript is to summarize information that was presented at this workshop, as well as the main points that emerged from the associated discussions.
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