Ebook Acceptance-based Intervention to promote HIV Medication Adherence

Human immunodeficiency virus (HIV) is a global health concern. In the U.S., rates of infection continue to rise in certain populations. HIV’s chronicity requires a lifelong vigilance to healthy living and safe practices. The challenge of living with HIV involves long-term, complex self-management by patients as well as required medical care and typically, supportive social services.

Maintaining treatment requires education, motivation, and effective problem solving skills. Extant literature has focused on general variables that may affect adherence to HIV treatment, and some empirical support for the efficacy of interventions promoting adherence has been documented.

However, no “gold standard” treatment has been achieved and it is unclear whether a standard protocol will emerge given the substantial differences among patients’ individual needs. The following sections describe these obstacles to good HIV care, and introduce a novel intervention designed to address the complex needs of this population.

Contents

LIST OF TABLES
LIST OF FIGURES
ABSTRACT
1. INTRODUCTION
1.1. Management of HIV

1.1.1. Overview
1.1.2. Pharmacological treatment
1.1.3. Adherence to HIV treatments
1.1.4. Summary and conclusions

1.2. Factors affecting adherence

1.2.1. Overview
1.2.2. Measuring adherence
1.2.3. Low socioeconomic status
1.2.4. Dominant models of health behavior
1.2.5. Thought suppression
1.2.6. HIV and stigma
1.2.7. Summary and conclusions

1.3. HAART adherence interventions

1.3.1. Preliminary reviews
1.3.2. Meta-analytic conclusions
1.3.3. Summary and conclusions

1.4. Acceptance-based approach to HIV medication adherence

1.4.1. Model of impact of emotional avoidance on HIV
1.4.2. Acceptance and Commitment Therapy
1.4.3. Summary and conclusions

1.5. Summary and study rationale
1.6. Statement of Purpose
1.7. Hypotheses: Evaluating the effects of an acceptance-based intervention to promote HIV medication adherence
2. METHOD
2.1. Participants
2.2. Measures

2.2.1. Pharmacy Refill Information
2.2.2. AIDS Clinical Trials Group Adherence Interview
2.2.3. Acceptance and Action Questionnaire-2
2.2.4. Beck Depression Inventory-II
2.2.5. Beck Anxiety Inventory
2.2.6. The Philadelphia Mindfulness Scale

2.3. Treatments
2.3.1. Alternate designs considered
2.4. Procedures
2.5. Statistical Analyses

2.5.1. Statistical Power
2.5.2. Preliminary analyses
2.5.3. Primary analyses
2.5.4. Secondary analyses

3. RESULTS
3.1. Sample description

3.1.1. Demographic variables
3.1.2. HIV variables

3.2. Preliminary analyses

3.2.1. Dropouts
3.2.2. Group equivalence through randomization

3.3. Primary analyses

3.3.1. Outcome measures
3.3.2. Overall group change
3.3.3. Process measures

3.4. Secondary analyses

3.4.1. Correlation analyses

4. DISCUSSION
4.1. Summary of Results

4.1.1. Qualitative Observations and Process

4.2. Support for Hypotheses

4.2.1. Hypothesis #1
4.2.2. Hypothesis #2
4.2.3. Hypothesis #3
4.2.4. Supplementary findings

4.3. Limitations
4.4. Implications and future directions
LIST OF REFERENCES
APPENDIX A: Acceptance-based Intervention Manual
VITA

Download
PDF Ebook Acceptance-based Intervention to promote HIV Medication Adherence